Tissue expression
Cell line expression
Protein structure
FBXL7
F-box and leucine rich repeat protein 7FBL6, FBL7, KIAA0840
This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domain (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Top validated antibodies |
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Novus Biologicals | NBP1-55053 | 2 references | Polyclonal |
WB
IP
IHC
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antibodies-online | ABIN4310745 | Polyclonal |
WB
IP
IHC
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Acris Antibodies GmbH | AP51623PU-N | Polyclonal |
WB
EL
FC
|
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Biorbyt | orb1241633 | Polyclonal |
WB
EL
IHC
|
||
Aviva Systems Biology | ARP43132_T100 | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Recommended by provider