Tissue expression
Cell line expression
Protein structure
BMP8A
Bone morphogenetic protein 8aOP-2
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| Cusabio Biotech Co., Ltd | Polyclonal |
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| LSBio | Polyclonal |
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| Biorbyt | Polyclonal |
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| R&D Systems | 1 references | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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