SNRNP35

The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant. [provided by RefSeq, Aug 2013]

Description

Small nuclear ribonucleoprotein U11/U12 subunit 35

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

12 (123458088 - 123473154)

Ensembl ID

ENSG00000184209  (ver. 103.38)

Orthologs

Mouse Snrnp35: ENSMUSG00000029402

UniProt

Q16560

neXtProt

NX_Q16560

Human splice variants
Mouse splice variants

Protein structure