CLECL1

This gene encodes a type II transmembrane, C-type lectin-like protein that is highly expressed on dendritic and B cells. This protein may act as a T-cell costimulatory molecule that enhances interleukin-4 production, and maybe involved in the regulation of the immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Description

C-type lectin like 1

Tissue specificity

Group enriched (intestine, lymphoid tissue)

Subcell location

Plasma membrane, Centriolar satellite

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins

Chromosome

12 (9715860 - 9733299)

Ensembl ID

ENSG00000184293  (ver. 103.38)

Orthologs

-

UniProt

Q8IZS7

neXtProt

NX_Q8IZS7

Human splice variants

Protein structure