Tissue expression
Cell line expression
Protein structure
GDF3
Growth differentiation factor 3This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]
Top validated antibodies |
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| R&D Systems | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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| Abnova Corporation | 3 references | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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