TAFA3

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Description

TAFA chemokine like family member 3

Tissue specificity

Group enriched (adrenal gland, retina)

Predicted location

Secreted in other tissues

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

1 (112720419 - 112727235)

Ensembl ID

ENSG00000184599  (ver. 103.38)

Orthologs

Mouse Tafa3: ENSMUSG00000055865

UniProt

Q7Z5A8

neXtProt

NX_Q7Z5A8

Human splice variants
Mouse splice variants

Protein structure