PRSS57

This gene encodes an arginine-specific serine protease and member of the peptidase S1 family of proteins. The encoded protein may undergo proteolytic activation before storage in azurophil granules, in neutrophil cells of the immune system. Following neutrophil activation, the protease is released into the pericellular environment, where it may play a role in defense against microbial pathogens. [provided by RefSeq, Jul 2016]

Description

Serine protease 57

Tissue specificity

Tissue enriched (bone marrow)

Predicted location

Secreted to blood

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

19 (685546 - 695498)

Ensembl ID

ENSG00000185198  (ver. 103.38)

Orthologs

Mouse Prss57: ENSMUSG00000020323

UniProt

Q6UWY2

neXtProt

NX_Q6UWY2

Human splice variants
Mouse splice variants

Protein structure