SFTPA2

This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009]

Description

Surfactant protein A2

Tissue specificity

Tissue enriched (lung)

Predicted location

Secreted in other tissues

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

10 (79555852 - 79560407)

Ensembl ID

ENSG00000185303  (ver. 103.38)

Orthologs

-

UniProt

Q8IWL1

neXtProt

NX_Q8IWL1

Human splice variants

Protein structure