Tissue expression
Cell line expression
Protein structure
FCAR
Fc fragment of IgA receptorCD89
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
GeneTex | GTX41763 | Monoclonal |
WB
EL
IP
FC
FA
|
||
Biorbyt | orb1727246 | Recombinant |
WB
ICC
IP
IHC
FC
|
||
antibodies-online | ABIN2472753 | 4 references | Monoclonal |
WB
EL
IP
FC |
|
Invitrogen Antibodies | MA1-72500 | 3 references | Monoclonal |
FC
RA
OA
|
|
Novus Biologicals | NB100-63266 | Monoclonal |
WB
EL
IP
FC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider