KCNK18

Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outward rectifying potassium channel. A mutation in this gene has been found to be associated with migraine with aura. [provided by RefSeq, Jan 2011]

Description

Potassium two pore domain channel subfamily K member 18

Tissue specificity

Tissue enhanced (choroid plexus)

Predicted location

Membrane

Protein family

Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Potential drug targets
Predicted membrane proteins
Voltage-gated ion channels

Chromosome

10 (117197489 - 117210299)

Ensembl ID

ENSG00000186795  (ver. 103.38)

Orthologs

Mouse Kcnk18: ENSMUSG00000040901

UniProt

Q7Z418

neXtProt

NX_Q7Z418

Human splice variants
Mouse splice variants

Protein structure