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NBR1
NBR1 autophagy cargo receptor1A1-3B, CA125, KIAA0049, M17S2
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Top validated antibodies |
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| Proteintech Group |  16004-1-AP |
47 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 16004-1-AP |
Polyclonal |
WB
ICC
IP
IHC
FC
OA
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| Novus Biologicals | H00004077-M01 |
12 references | Monoclonal |
WB
EL
ICC
IEM
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| LSBio | LS-C332925 |
Polyclonal |
WB
ICC
IP
IHC
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| NovoPro Bioscience Inc. | 113023 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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