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DPYD
Dihydropyrimidine dehydrogenaseDPD
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Top validated antibodies |
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| Novus Biologicals |  H00001806-M01 |
1 references | Monoclonal |
WB
EL
ICC
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| LSBio | LS-C186323 |
Polyclonal |
WB
IHC
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| antibodies-online | ABIN560640 |
1 references | Monoclonal |
WB
EL
ICC
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| Invitrogen Antibodies | PA5-22302 |
1 references | Polyclonal |
WB
IHC
OA
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| Proteintech Group | 27662-1-AP |
2 references | Polyclonal |
WB
EL
IHC
|
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