Tissue expression
Cell line expression
Protein structure
HMGB1
High mobility group box 1DKFZp686A04236, HMG1, HMG3, SBP-1
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
8 references | Polyclonal |
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Novus Biologicals | ![]() |
14 references | Monoclonal |
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Proteintech Group | ![]() |
238 references | Polyclonal |
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antibodies-online | ![]() |
13 references | Polyclonal |
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R&D Systems | ![]() |
16 references | Monoclonal |
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