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AKR1C4
Aldo-keto reductase family 1 member C43-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  H00001109-M01 |
2 references | Monoclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | H00001109-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C375178 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN560358 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | H00001109-M01 |
Monoclonal |
WB
EL
ICC
IHC
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