Tissue expression
Cell line expression
Protein structure
CD247
CD247 moleculeCD3H, CD3Q, CD3Z
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 7 references | Polyclonal |
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| Invitrogen Antibodies | Monoclonal |
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| antibodies-online | 3 references | Monoclonal |
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| OriGene | Monoclonal |
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| GeneTex | Monoclonal |
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