AWAT1

The protein encoded by this gene belongs to the diacylglycerol acyltransferase family. It esterifies long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that this enzyme plays a central role in lipid metabolism in skin. Consistent with this observation, this protein is predominantly expressed in the sebaceous gland of the skin. [provided by RefSeq, Sep 2009]

Description

Acyl-CoA wax alcohol acyltransferase 1

Tissue specificity

Tissue enhanced (skin)

Predicted location

Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins

Chromosome

X (70234655 - 70240659)

Ensembl ID

ENSG00000204195  (ver. 103.38)

Orthologs

Mouse Awat1: ENSMUSG00000015665

UniProt

Q58HT5

neXtProt

NX_Q58HT5

Human splice variants
Mouse splice variants

Protein structure