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Protein structure
RNPS1
RNA binding protein with serine rich domain 1This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Top validated antibodies |
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| Proteintech Group |  10555-1-AP |
4 references | Polyclonal |
WB
EL
ICC
IP
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| Invitrogen Antibodies | 10555-1-AP |
Polyclonal |
WB
ICC
IP
OA
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| Novus Biologicals | H00010921-M05 |
1 references | Monoclonal |
WB
EL
IP
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| Atlas Antibodies | HPA044014 |
1 references | Polyclonal |
WB
ICC
IHC
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| NovoPro Bioscience Inc. | 114772 |
Polyclonal |
WB
EL
ICC
IP
|
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