NPTXR

This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]

Description

Neuronal pentraxin receptor

Tissue specificity

Tissue enriched (brain)

Subcell location

Nucleoplasm, Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

22 (38818452 - 38844028)

Ensembl ID

ENSG00000221890  (ver. 103.38)

Orthologs

Mouse Nptxr: ENSMUSG00000022421

UniProt

O95502

neXtProt

NX_O95502

Human splice variants
Mouse splice variants

Protein structure