APOC4-APOC2

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]

Description

APOC4-APOC2 readthrough (NMD candidate)

Tissue specificity

Tissue enriched (liver)

Predicted location

Membrane

Protein family

Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

19 (44942238 - 44949565)

Ensembl ID

ENSG00000224916  (ver. 103.38)

Orthologs

-

UniProt

 

neXtProt

 

Human splice variants

Protein structure