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Protein structure
LTB
Lymphotoxin betap33, TNFC, TNFSF3
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio |  LS-C356159 |
Polyclonal |
WB
ICC
IHC
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| Abnova Corporation | PAB17378 |
3 references | Polyclonal |
WB
ICC
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| antibodies-online | ABIN484458 |
1 references | Polyclonal |
WB
EL
ICC
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| GeneTex | GTX87332 |
Polyclonal |
WB
EL
ICC
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| St John's Laboratory | STJ93966 |
Polyclonal |
WB
EL
ICC
IHC
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