Tissue expression
Cell line expression
Protein structure
BGLAP
Bone gamma-carboxyglutamate proteinOCN
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
Top validated antibodies |
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R&D Systems | MAB1419 | 23 references | Monoclonal |
ICC
IHC
FC
|
|
GeneTex | GTX13418 | 5 references | Monoclonal |
WB
EL
ICC
IHC |
|
Novus Biologicals | MAB1419 | 24 references | Monoclonal |
ICC
IHC
FC
|
|
Invitrogen Antibodies | PA5-96529 | 1 references | Polyclonal |
WB
ICC
IHC
OA |
|
Proteintech Group | 23418-1-AP | 65 references | Polyclonal |
EL
ICC
IHC
|
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