TNFSF12-TNFSF13

This gene encodes a member of the tumor necrosis factor superfamily. It encodes a hybrid protein composed of the cytoplasmic and transmembrane domains of family member 12 fused to the C-terminal domain of family member 13. The hybrid protein is membrane anchored and presents the receptor-binding domain of family member 13 at the cell surface. It stimulates cycling in T- and B-lymphoma cell lines. [provided by RefSeq, Jul 2008]

Description

TNFSF12-TNFSF13 readthrough

Tissue specificity

Tissue enhanced (brain, choroid plexus)

Subcell location

Vesicles

Predicted location

Intracellular

Protein family

Predicted intracellular proteins

Chromosome

17 (7549099 - 7561601)

Ensembl ID

ENSG00000248871  (ver. 103.38)

Orthologs

Mouse Tnfsfm13: ENSMUSG00000018752

UniProt

 

neXtProt

 

Human splice variants
Mouse splice variants

Protein structure