TMED7-TICAM2

This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010]

Description

TMED7-TICAM2 readthrough

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Predicted intracellular proteins

Chromosome

5 (115578642 - 115626161)

Ensembl ID

ENSG00000251201  (ver. 103.38)

Orthologs

-

UniProt

 

neXtProt

 

Human splice variants

Protein structure