RGS21

Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination. [supplied by OMIM, Nov 2008]

Description

Regulator of G protein signaling 21

Tissue specificity

Not detected

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

1 (192316992 - 192367285)

Ensembl ID

ENSG00000253148  (ver. 103.38)

Orthologs

Mouse Rgs21: ENSMUSG00000098509

UniProt

Q2M5E4

neXtProt

NX_Q2M5E4

Human splice variants
Mouse splice variants

Protein structure