CHST7

This gene belongs to the sulfotransferase gene family. Sulfotransferases generate sulfated glycosaminoglycan (GAG) moities during chondroitin sulfate biosynthesis. They create considerable structural diversity among chondroitin sulfates by transferring sulfate with remarkable specificity for the underlying oligosaccharide substrate. This gene product mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of this gene family may be an important determinant of sulfated GAGs expression and the associated function of chondroitin sulfates as regulators of many biologic processes. This gene is part of a gene cluster on chromosome Xp11.23. [provided by RefSeq, Jul 2008]

Description

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7

Protein family

Enzymes, Secreted proteins predicted by MDSP

Chromosome

X:p11.23 (46433219 - 46457843)

Ensembl ID

ENSG00000147119  (ver. 69.37)

Orthologs

Mouse Chst7: ENSMUSG00000037347

Human splice variants
Mouse splice variants