CCKBR

This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Jul 2008]

Description

cholecystokinin B receptor

Protein family

Candidate cancer biomarkers, G-protein coupled receptors, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins

Chromosome

11:p15.4 (6280966 - 6293357)

Ensembl ID

ENSG00000110148  (ver. 71.37)

Orthologs

Mouse Cckbr: ENSMUSG00000030898

Human splice variants
Mouse splice variants