CACNA1G

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]

Description

calcium channel, voltage-dependent, T type, alpha 1G subunit

Protein family

Membrane proteins predicted by MDM, Voltage-gated ion channels

Chromosome

17:q21.33 (48638429 - 48704835)

Ensembl ID

ENSG00000006283  (ver. 69.37)

Orthologs

Mouse Cacna1g: ENSMUSG00000020866

Human splice variants
Mouse splice variants