CALCR

This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Description

calcitonin receptor

Protein family

G-protein coupled receptors, Mapped to UniProt SWISS-PROT, Mutated genes in cancer, Potential transmembrane proteins, Potentially secreted proteins, Transporters

Chromosome

7:q21.3 (93053799 - 93204042)

Ensembl ID

ENSG00000004948  (ver. 71.37)

Orthologs

Mouse Calcr: ENSMUSG00000023964

Human splice variants
Mouse splice variants