FHL1

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described. [provided by RefSeq, Nov 2009]

Description

four and a half LIM domains 1

Protein family

Secreted proteins predicted by MDSP

Chromosome

X:q26.3 (135229559 - 135293518)

Ensembl ID

ENSG00000022267  (ver. 69.37)

Orthologs

Mouse Fhl1: ENSMUSG00000023092

Human splice variants
Mouse splice variants