HCFC2

This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]

Description

host cell factor C2

Protein family

Mapped to UniProt SWISS-PROT, Potential transmembrane proteins

Chromosome

12:q23.3 (104458235 - 104498639)

Ensembl ID

ENSG00000111727  (ver. 71.37)

Orthologs

Mouse Hcfc2: ENSMUSG00000020246

Human splice variants
Mouse splice variants