P2RY14

The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

Description

purinergic receptor P2Y, G-protein coupled, 14

Protein family

G-protein coupled receptors, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins

Chromosome

3:q25.1 (150929905 - 150996255)

Ensembl ID

ENSG00000174944  (ver. 71.37)

Orthologs

Mouse P2ry14: ENSMUSG00000036381

Human splice variants
Mouse splice variants