ASIC4

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]

Description

acid-sensing (proton-gated) ion channel family member 4

Protein family

Mapped to UniProt SWISS-PROT, Potential transmembrane proteins, Potentially secreted proteins

Chromosome

2:q35 (220378892 - 220403494)

Ensembl ID

ENSG00000072182  (ver. 71.37)

Orthologs

Mouse Accn4: ENSMUSG00000033007

Human splice variants
Mouse splice variants