ADCK3

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Description

aarF domain containing kinase 3

Protein family

Kinases

Chromosome

1:q42.13 (227085237 - 227175246)

Ensembl ID

ENSG00000163050  (ver. 69.37)

Orthologs

Mouse Adck3: ENSMUSG00000026489

Human splice variants
Mouse splice variants