ARID4B

This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

Description

AT rich interactive domain 4B (RBP1-like)

Protein family

-

Chromosome

1:q42.3 (235294949 - 235491534)

Ensembl ID

ENSG00000054267  (ver. 69.37)

Orthologs

Mouse Arid4b: ENSMUSG00000039219

Human splice variants
Mouse splice variants