LYNX1

This gene encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Functional analysis indicates that this protein is not a ligand or neurotransmitter but has the capacity to enhance nicotinic acetylcholine receptor function in the presence of acetylcholine. This gene may also play a role in the pathogenesis of psoriasis vulgaris. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Description

Ly6/neurotoxin 1

Protein family

Membrane proteins predicted by MDM, Secreted proteins predicted by MDSP, Transporters

Chromosome

8:q24.3 (143845752 - 143859640)

Ensembl ID

ENSG00000180155  (ver. 69.37)

Orthologs

Mouse 2300005B03Rik: ENSMUSG00000075605

Human splice variants
Mouse splice variants