ABCG1

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]

Description

ATP-binding cassette, sub-family G (WHITE), member 1

Protein family

Mapped to UniProt SWISS-PROT, Potential transmembrane proteins, Potentially secreted proteins, Transporters

Chromosome

21:q22.3 (43619799 - 43717354)

Ensembl ID

ENSG00000160179  (ver. 71.37)

Orthologs

Mouse Abcg1: ENSMUSG00000024030

Human splice variants
Mouse splice variants