CA14

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008]

Description

carbonic anhydrase XIV

Protein family

Enzymes, Membrane proteins predicted by MDM, Secreted proteins predicted by MDSP

Chromosome

1:q21.2 (150230169 - 150237478)

Ensembl ID

ENSG00000118298  (ver. 69.37)

Orthologs

Mouse Car14: ENSMUSG00000038526

Human splice variants
Mouse splice variants