KCNV2

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]

Description

potassium channel, subfamily V, member 2

Protein family

Membrane proteins predicted by MDM, Voltage-gated ion channels

Chromosome

9:p24.2 (2717502 - 2730037)

Ensembl ID

ENSG00000168263  (ver. 69.37)

Orthologs

Mouse Kcnv2: ENSMUSG00000047298

Human splice variants
Mouse splice variants