SENP3
gene productDKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]). [supplied by OMIM, Jun 2009]
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 Thermo Fisher Scientific Pierce |
PA5-31055 | 0 references | Polyclonal |
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