VIMP

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Description

VCP-interacting membrane protein

Protein family

Membrane proteins predicted by MDM, Transporters

Chromosome

15:q26.3 (101811022 - 101817705)

Ensembl ID

ENSG00000131871  (ver. 69.37)

Orthologs

Mouse H47: ENSMUSG00000075701

Human splice variants
Mouse splice variants