MAK

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Description

male germ cell-associated kinase

Protein family

Enzymes, Kinases

Chromosome

6:p24.2 (10762956 - 10838764)

Ensembl ID

ENSG00000111837  (ver. 69.37)

Orthologs

Mouse Mak: ENSMUSG00000021363

Human splice variants
Mouse splice variants