ADH7

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Description

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Protein family

Enzymes

Chromosome

4:q23 (100333418 - 100356894)

Ensembl ID

ENSG00000196344  (ver. 69.37)

Orthologs

Mouse Adh7: ENSMUSG00000055301

Human splice variants
Mouse splice variants