ASNA1

This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion. [provided by RefSeq, Oct 2011]

Description

arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

Protein family

Mapped to UniProt SWISS-PROT, Potentially secreted proteins, Transporters

Chromosome

19:p13.2 (12847953 - 12859137)

Ensembl ID

ENSG00000198356  (ver. 71.37)

Orthologs

Mouse Asna1: ENSMUSG00000052456

Human splice variants
Mouse splice variants