AGPAT1

This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Description

1-acylglycerol-3-phosphate O-acyltransferase 1

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins, Potentially secreted proteins

Chromosome

6:p21.32 (32135989 - 32145873)

Ensembl ID

ENSG00000204310  (ver. 71.37)

Orthologs

Mouse Agpat1: ENSMUSG00000034254

Human splice variants
Mouse splice variants