KCNB1

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]

Description

potassium voltage-gated channel, Shab-related subfamily, member 1

Protein family

Membrane proteins predicted by MDM, Transporters, Voltage-gated ion channels

Chromosome

20:q13.13 (47984946 - 48099184)

Ensembl ID

ENSG00000158445  (ver. 69.37)

Orthologs

Mouse Kcnb1: ENSMUSG00000050556

Human splice variants
Mouse splice variants