FZD10

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]

Description

frizzled family receptor 10

Protein family

CD markers, G-protein coupled receptors, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins, Potentially secreted proteins

Chromosome

12:q24.33 (130647004 - 130650285)

Ensembl ID

ENSG00000111432  (ver. 71.37)

Orthologs

Mouse Fzd10: ENSMUSG00000081683

Human splice variants
Mouse splice variants