CCR6

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

Description

chemokine (C-C motif) receptor 6

Protein family

CD markers, GPCRs excl olfactory receptors, Membrane proteins predicted by MDM

Chromosome

6:q27 (167525295 - 167553184)

Ensembl ID

ENSG00000112486  (ver. 69.37)

Orthologs

Mouse Ccr6: ENSMUSG00000040899

Human splice variants
Mouse splice variants