HTR1A

This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]

Description

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Protein family

G-protein coupled receptors, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins

Chromosome

5:q12.3 (63256183 - 63258334)

Ensembl ID

ENSG00000178394  (ver. 71.37)

Orthologs

Mouse Htr1a: ENSMUSG00000021721

Human splice variants
Mouse splice variants