ADAMTS9

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. [provided by RefSeq, Jul 2008]

Description

ADAM metallopeptidase with thrombospondin type 1 motif, 9

Protein family

Candidate cancer biomarkers, Mapped to UniProt SWISS-PROT, Peptidases, Potentially secreted proteins

Chromosome

3:p14.1 (64501333 - 64673676)

Ensembl ID

ENSG00000163638  (ver. 71.37)

Orthologs

Mouse Adamts9: ENSMUSG00000030022

Human splice variants
Mouse splice variants