ABCA9

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]

Description

ATP-binding cassette, sub-family A (ABC1), member 9

Protein family

Membrane proteins predicted by MDM

Chromosome

17:q24.2 (66970629 - 67057205)

Ensembl ID

ENSG00000154258  (ver. 69.37)

Orthologs

Mouse Abca9: ENSMUSG00000041797

Human splice variants
Mouse splice variants